Live Attenuated Hepatitis A Vaccine Side Effects

Receiving a live attenuated hepatitis A vaccine is generally safe and effective in preventing hepatitis A infection. However, like any medical intervention, it may cause some side effects in certain individuals. These reactions are typically mild and short-lived, resolving on their own without the need for medical intervention.

Common Side Effects

One of the most frequently reported side effects is localized pain and tenderness at the injection site. This usually occurs within the first 24 hours after vaccination and typically subsides within two to three days. Applying a cool compress and moving the arm gently can help alleviate discomfort.

Mild Fever and General Discomfort

Within one to two weeks following vaccination, some individuals may experience a temporary fever. This reaction is usually mild and lasts for one to two days. Staying hydrated, getting plenty of rest, and dressing warmly can help prevent secondary infections. If the fever is moderate or lasts longer than 48 hours, over-the-counter medications or physical cooling methods may be used to manage symptoms. In rare cases of high fever, medical attention should be sought to prevent complications such as febrile seizures.

Skin Rashes

Occasionally, recipients may develop a mild rash after vaccination. These skin reactions are generally not serious and tend to fade on their own. If needed, symptomatic treatment under the guidance of a healthcare provider can be considered.

Severe Allergic Reactions

While extremely rare, some individuals may experience serious allergic reactions, including anaphylactic shock, allergic rash, Henoch-Schönlein purpura, or other immune-related conditions such as acute febrile polyneuropathy, brachial plexopathy, transverse myelitis, and erythema multiforme. These symptoms require immediate medical evaluation and treatment at a qualified healthcare facility.