Chronic Atrophic Gastritis: Effective Treatment Strategies

Chronic atrophic gastritis is a long-term condition that involves the gradual loss of gastric glandular cells and their replacement with intestinal or fibrous tissues. Managing this condition effectively requires a comprehensive approach that includes medication, lifestyle adjustments, and in some cases, antibiotic therapy.

Medications for Symptom Relief and Healing

One of the primary treatment strategies involves the use of gastric mucosal protectants, which help shield the stomach lining from further damage and promote healing. Commonly used medications include antacids like aluminum magnesium carbonate and sodium bicarbonate, which can help neutralize stomach acid and reduce discomfort.

In addition to protective agents, doctors often prescribe prokinetic drugs such as cisapride to improve gastrointestinal motility. These medications help regulate digestion and reduce symptoms like bloating and delayed gastric emptying.

Antibiotic Therapy for H. pylori Infection

Diagnosis and Targeted Treatment

If a patient tests positive for Helicobacter pylori (H. pylori), a common bacterial infection linked to chronic gastritis, a course of antibiotics is usually recommended. This infection can worsen the condition of the gastric mucosa and delay healing.

To confirm the presence of H. pylori, a breath test or stool test may be performed. Once diagnosed, treatment typically involves a combination of antibiotics such as amoxicillin and gentamicin, often alongside bismuth-containing compounds or other antimicrobial agents like compound berberine.

Lifestyle and Dietary Modifications

Alongside medical treatment, making appropriate lifestyle changes is crucial for long-term management. Patients should maintain a regular eating schedule and avoid skipping meals, which can help regulate gastric acid secretion.

It's also important to avoid stimulating foods and medications such as spicy dishes, caffeine, and nonsteroidal anti-inflammatory drugs (NSAIDs), which can irritate the stomach lining. Emotional stress should be minimized through relaxation techniques or counseling, as stress can exacerbate digestive issues.

Finally, quitting smoking and avoiding alcohol are essential steps in preventing further damage to the gastric mucosa and reducing the risk of complications such as peptic ulcers or even gastric cancer in the long term.