Gastric And Duodenal Ulcer Symptoms: Understanding The Differences And Treatment Options

One of the most common characteristics of gastric ulcers is stomach pain that occurs after eating. This discomfort typically arises due to the interaction of stomach acid with the exposed ulcerated area in the stomach lining. On the other hand, duodenal ulcers often cause significant pain when the stomach is empty, particularly during the night, as acid secretion increases without the presence of food to neutralize it.

Common Symptoms Of Gastric And Duodenal Ulcers

While there are distinct differences in when the pain occurs, both gastric and duodenal ulcers share several similar symptoms. These include bloating, nausea, belching, and a persistent unpleasant taste in the mouth. These symptoms can vary in intensity and may come and go over time, often worsening during periods of stress or after consuming certain foods and beverages.

Understanding The Underlying Cause

Both conditions develop when the balance between aggressive factors—like stomach acid and pepsin—and the protective mechanisms of the mucosal lining is disrupted. When the mucosal protection is weakened, the lining becomes more vulnerable to damage from gastric acid, leading to ulcer formation.

Effective Treatment Approaches

Treating gastric and duodenal ulcers usually involves a dual approach: reducing acid production and strengthening the protective lining of the stomach and intestines. Proton pump inhibitors (PPIs) such as omeprazole or pantoprazole are commonly prescribed to significantly lower acid secretion. Alongside PPIs, mucosal protective agents like sucralfate or bismuth subsalicylate may be used to coat the ulcer and shield it from further irritation.

Addressing Helicobacter Pylori Infection

If testing confirms the presence of Helicobacter pylori (H. pylori), a bacterium commonly associated with peptic ulcers, a course of antibiotics is added to the treatment plan. This typically includes a combination of amoxicillin and clarithromycin, which work together to eliminate the infection and reduce the chances of ulcer recurrence.