What Is the Preferred Diagnostic Test for Duodenal Ulcers

One of the most common types of peptic ulcers occurs in the duodenum, particularly in the duodenal bulb or just beyond it. The most accurate and widely recommended method for diagnosing duodenal ulcers is gastroscopy, which is considered the gold standard in medical evaluation. This procedure allows doctors to directly visualize the lining of the duodenum and identify any ulcerations or abnormalities.

Why Gastroscopy Is Essential

Duodenal ulcers often develop in the bulb area due to the thin walls and high exposure to gastric acid. These ulcers can lead to complications such as bleeding, perforation, narrowing of the intestinal passage, or even obstruction. Understanding the nature of duodenal ulcers, especially their characteristic pattern of pain—typically a burning sensation that worsens when the stomach is empty and improves after eating—is crucial for timely diagnosis and treatment.

Connection Between H. pylori and Ulcer Recurrence

There is a strong correlation between duodenal ulcers and infection with Helicobacter pylori (H. pylori), with studies suggesting that up to 95% of duodenal ulcer cases are linked to this bacterial infection. H. pylori is also a leading cause of ulcer recurrence. Therefore, during a gastroscopy exam, it is highly recommended to perform a test for H. pylori using either a carbon-13 or carbon-14 breath test.

Importance of Targeted Treatment

If the H. pylori test returns positive, it's important to undergo a comprehensive and medically supervised treatment plan. This typically includes a combination of antibiotics and acid-suppressing medications. Proper treatment not only alleviates symptoms but also significantly increases the chances of a full recovery and reduces the risk of future complications.