Women And Gallbladder Inflammation: Understanding The Causes

Gallbladder disease, which includes both acute and chronic cholecystitis, refers to the inflammatory process that occurs in the gallbladder due to various factors. Women are particularly susceptible to this condition, and there are several key causes behind its development.

Acute Calculous Cholecystitis is one of the primary types and is often linked to gallstones. Initially, the inflammation may result from direct physical damage to the mucosal lining caused by stones pressing against the gallbladder walls. Later, bacterial infection can develop, especially when bile flow is obstructed and stagnates inside the gallbladder.

Another serious form is Acute Acalculous Cholecystitis, which occurs without the presence of gallstones. This type is mainly caused by bile stasis and reduced blood flow to the gallbladder. Because the condition progresses rapidly, it carries a higher risk of complications such as gangrene and perforation of the gallbladder.

Chronic Calculous Cholecystitis typically develops over time and is associated with repeated episodes of inflammation. The main causes include gallbladder stones and bacterial infections. Dietary habits also play a significant role — a low-fiber, high-calorie diet can increase cholesterol levels in bile, promoting stone formation. Certain medications, like ceftriaxone and oral contraceptives, may also contribute to gallstone development. Additionally, rapid weight loss, especially through extreme dieting, can increase the risk of forming gallstones.

Lastly, Chronic Acalculous Cholecystitis is mainly triggered by infections, particularly those of intestinal origin. Parasites and viruses, such as roundworms and trichomonads, can also be contributing factors. Other causes include impaired gallbladder emptying, reduced blood supply to the gallbladder, and metabolic disturbances that lead to chemical irritation and chronic inflammation.