Gallbladder Inflammation Can Cause Pain During Inhalation

Gallbladder inflammation, or cholecystitis, can lead to significant discomfort, particularly during deep inhalation. This symptom is often linked to a clinical sign known as Murphy's sign. During a physical examination, a healthcare provider places their thumb under the right rib cage and asks the patient to take a deep breath. If the patient abruptly stops inhaling due to pain, it is considered a positive Murphy's sign.

This reaction occurs because the inflamed gallbladder expands during inhalation, coming into contact with the examiner's thumb. The pressure from this contact causes sharp pain, prompting the patient to halt their breath. The same mechanism can cause pain when the gallbladder presses against the abdominal wall during deep breathing, especially in cases of significant gallbladder swelling.

However, it's important to note that pain during inhalation is not exclusive to gallbladder disease. Other potential causes include pulmonary conditions such as pneumonia or pleurisy. Additionally, musculoskeletal issues like rib fractures or trauma should be considered in the diagnostic process.

Therefore, when a patient experiences pain during inhalation, it is crucial to evaluate not only the gallbladder but also other organs in the right upper quadrant of the abdomen. A comprehensive approach ensures accurate diagnosis and appropriate treatment.