Treatment Options for Bile Reflux Gastritis

Bile reflux gastritis is a condition commonly identified during endoscopic examinations. If left untreated, it can lead to significant discomfort and long-term damage to the stomach lining. Managing this condition involves addressing both bile reflux and gastric acid secretion, while also supporting the healing of the gastric mucosa.

One of the first steps in treatment involves using medications that neutralize bile. A commonly prescribed option is hydrotalcid, which helps bind bile acids and reduce their harmful effects on the stomach lining. In addition, proton pump inhibitors (PPIs) such as esomeprazole, lansoprazole, or rebamipide are often used to suppress acid production. These medications help create a less acidic environment in the stomach, which promotes healing of the damaged mucosa.

If symptoms persist despite using these two types of medications, adding a prokinetic agent may be necessary to improve gastric motility. Drugs like domperidone, mosapride, cisapride, or itopride can help speed up gastric emptying and reduce the likelihood of bile flowing back into the stomach.

Bile contains bile acids and salts, which are normally released into the small intestine to aid in fat digestion. However, when they reflux into the stomach, they can irritate and erode the gastric mucosa. Combined with high levels of stomach acid, this creates a harsh environment that can lead to inflammation, ulcers, and even precancerous changes over time.

Managing bile reflux effectively requires a comprehensive approach that includes lifestyle changes, dietary adjustments, and appropriate medication use. Patients should also consult with a gastroenterologist to monitor progress and adjust treatment plans as needed.