Is Autoimmune Hepatitis Treatable?

Autoimmune hepatitis is considered a relatively challenging condition to manage. Similar to other autoimmune diseases, it occurs when the body's immune system becomes dysregulated and begins attacking healthy organs and cells without discrimination, leading to a range of pathological changes.

This condition shares symptoms with viral hepatitis, such as jaundice, bloating, abdominal pain, skin itching, and discomfort in the upper abdomen. However, these symptoms are not unique to autoimmune hepatitis. When this condition is suspected, doctors may perform a series of tests including comprehensive immune panels, such as rheumatoid and lupus screenings, as well as imaging studies like CT scans, ultrasounds, or MRIs. While these tests can reveal abnormalities, the only definitive way to diagnose autoimmune hepatitis is through a liver biopsy, where a small sample of liver tissue is examined under a microscope.

Treatment typically involves the use of immunosuppressive medications, such as prednisone or corticosteroids, to reduce the abnormal immune response. Additional medications like compound glycyrrhizinic acid or reduced glutathione may be used to support liver function. In many cases, these treatments can bring liver enzyme levels back to normal. However, autoimmune hepatitis has a high rate of recurrence, even after successful treatment.

Repeated flare-ups can lead to serious complications, including progressive liver damage, cirrhosis, and an increased risk of developing liver cancer. Long-term monitoring and management are essential for patients to maintain liver health and prevent severe outcomes. Early diagnosis and consistent follow-up care significantly improve the prognosis for individuals living with this condition.