Hepatitis C Virus Antibody Level of 0.05 S/CO: What Does It Mean?

A hepatitis C virus (HCV) antibody level of 0.05 S/CO indicates a very low value, which is typically interpreted as a negative result. This means that there is no significant evidence of exposure to the hepatitis C virus based on antibody testing alone. When a person is infected with HCV, their immune system produces specific antibodies to fight the virus. Therefore, antibody testing is commonly used as a screening method to determine whether someone has been exposed to HCV.

However, a positive antibody test does not necessarily mean that the virus is currently present in the body. It only suggests a past exposure. To confirm an active infection, a follow-up test for HCV RNA (the virus's genetic material) is necessary. This test detects whether the virus is actively replicating in the body, which indicates a current infection requiring medical attention.

Routine health screenings often include HCV antibody testing to identify individuals who may have been exposed to the virus. For high-risk groups—such as those with a history of blood transfusions, blood product use, or plasma donation, as well as long-term hemodialysis patients and individuals with Factor VIII deficiency (hemophilia)—both HCV antibody and HCV RNA tests are recommended. This dual-testing approach ensures more accurate and comprehensive screening for hepatitis C in at-risk populations.

By combining both antibody and RNA testing, healthcare providers can more effectively identify and manage hepatitis C infections, especially in individuals with ongoing exposure risks.