Cholestatic Hepatitis: Is It Curable?

Cholestatic hepatitis, a special clinical type of viral hepatitis, is indeed treatable. Patients often experience symptoms such as jaundice of the skin and sclera, skin itching, and light-colored stools, sometimes appearing pale or clay-like. These symptoms may be accompanied by loss of appetite and abdominal bloating. Liver function tests typically show elevated bilirubin levels, primarily in the form of direct bilirubin, with only a mild increase in transaminase levels or no significant elevation at all. Additionally, gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP) levels may rise, while albumin levels may remain stable or show only a slight decrease. Coagulation function usually remains normal, and ultrasound imaging may reveal mild liver enlargement.

Recommended dietary adjustments are essential for managing this condition. Patients should follow a light diet and avoid animal fats, minimizing the intake of meat products. However, they can safely consume dairy products, eggs, and milk. Due to impaired bile secretion in cholestatic hepatitis, consuming fatty foods may worsen upper abdominal discomfort and should be avoided to prevent aggravating symptoms.

Proper treatment involves rest and medication. Bed rest is recommended to support recovery, along with the use of anti-inflammatory, liver-protecting, and bile-stimulating drugs. Glycyrrhizin compounds are commonly used for their anti-inflammatory and hepatoprotective properties. Medications such as S-adenosylmethionine and ursodeoxycholic acid are also prescribed to help reduce jaundice and improve bile flow.

Despite a longer recovery period, full recovery is achievable with timely and appropriate treatment. While the course of the disease may take more time compared to other forms of hepatitis, most patients can expect a complete recovery if they follow medical advice and maintain a healthy lifestyle during and after treatment. Early diagnosis and consistent management play a crucial role in achieving positive outcomes.

In conclusion, cholestatic hepatitis is a treatable condition, and with the right medical care and lifestyle modifications, patients can expect to regain their health without long-term complications.