Can Hepatitis B Be Cured?

Hepatitis B can be managed and in some cases considered cured based on clinical standards. Clinical remission refers to the stage where the virus becomes inactive, liver damage halts its progression, and the risks of complications such as cirrhosis and liver cancer are significantly reduced. This outcome can be achieved through long-term and consistent treatment.

There are two main perspectives on curing Hepatitis B: clinical cure and virological cure. A virological cure means complete elimination of the hepatitis B virus from the body. While there is currently no specific medication that guarantees total viral clearance, a small percentage of patients naturally achieve this state each year, marked by the loss of the hepatitis B surface antigen (HBsAg).

Long-term antiviral medications are the most common treatment method. Drugs such as entecavir and tenofovir are effective at suppressing viral replication and preventing liver damage. These medications are usually taken orally on a daily basis and may be required for many years or even lifelong.

In some cases, interferon therapy can also help achieve viral clearance. Both long-acting and short-acting interferons are used in treatment, and some patients respond well enough to reach the goal of eliminating the surface antigen.

Regular monitoring and personalized treatment plans are essential for managing Hepatitis B effectively. Patients should work closely with their healthcare providers to determine the best course of action based on their specific condition and response to therapy.