Can Fatty Liver Cause Elevated Transaminase Levels?

Fatty liver disease can lead to increased levels of transaminase, especially when it progresses to non-alcoholic steatohepatitis (NASH). Fatty liver occurs when the body's lipid metabolism becomes disrupted, causing fat to accumulate within liver cells. This buildup of fat leads to a condition known as hepatic steatosis or fatty liver disease.

When fat accumulates excessively in the liver, it can cause inflammation and damage to liver cells. If the condition worsens, liver cell necrosis may occur, which results in the release of enzymes such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) into the bloodstream. These elevated enzyme levels are often detected during routine liver function tests and indicate liver damage.

At this stage, the condition has likely progressed to fatty liver inflammation, or steatohepatitis, which requires medical attention. Managing fatty liver involves a combination of lifestyle changes and, in some cases, medication to protect liver function. Without proper intervention, continued liver damage can lead to fibrosis or even cirrhosis over time.

To prevent the progression of fatty liver disease, it is essential to adopt a healthy lifestyle. Key strategies include maintaining a balanced diet, engaging in regular physical activity, and avoiding alcohol and other liver-damaging substances. Additionally, managing underlying conditions such as obesity, diabetes, and high cholesterol is crucial in reducing the risk of liver damage.

In summary, elevated transaminase levels can be a sign that fatty liver has progressed to a more serious stage. Early detection and lifestyle modification are vital in preventing further liver injury and promoting long-term health.