ALT Levels in Fatty Liver Disease

Fatty liver disease often leads to a mild increase in ALT (Alanine Aminotransferase), which is an enzyme found primarily in the liver. In most cases, ALT levels rise to between 2 and 10 times the upper limit of the normal range. For many patients with fatty liver, ALT values typically fall within the range of 120 to 400 U/L, although it is uncommon for levels to exceed 400 U/L.

Elevated ALT levels suggest liver damage or inflammation, which is commonly seen in non-alcoholic fatty liver disease (NAFLD) or alcoholic fatty liver disease. Managing this condition involves a combination of lifestyle changes and medical treatment. Adopting a balanced diet, engaging in regular physical activity, and maintaining a healthy weight are essential steps in reducing liver enzyme levels.

In addition to lifestyle modifications, doctors may prescribe medications that support liver function and reduce enzyme levels. Commonly used drugs include Silybin (milk thistle extract), Compound Glycyrrhizinic Acid, Dipotassium Glycyrrhizinate, and Reduced Glutathione. These medications help protect liver cells and promote the normalization of ALT levels.

Monitoring ALT regularly is important for tracking liver health and assessing the effectiveness of treatment. While elevated ALT is a sign of liver stress, it's reassuring that with proper management, levels can often return to normal over time. However, persistent elevation may require further investigation to rule out more serious liver conditions.