Fatty Liver And Its Impact On Liver Function Tests

Fatty liver disease can lead to abnormal liver function test results. This condition is categorized into different stages including simple fatty liver, fatty liver inflammation (steatohepatitis), fatty liver fibrosis, and fatty liver cirrhosis. Simple fatty liver typically does not cause liver enzyme abnormalities and is often detected through imaging tests like ultrasound or CT scans. However, in cases of fatty liver inflammation, liver enzymes such as ALT (alanine aminotransferase), AST (aspartate aminotransferase), GGT (gamma-glutamyl transferase), and ALP (alkaline phosphatase) are often elevated. In more severe cases, bilirubin levels may also increase.

When liver function tests show abnormalities, it is important to address the underlying causes. If the condition is linked to obesity, metabolic syndrome, diabetes, or high cholesterol, lifestyle changes such as weight loss, improved diet, and increased physical activity are essential. Managing blood sugar and lipid levels can significantly improve liver health. If alcohol consumption is the cause, complete abstinence is strongly recommended. Similarly, if certain medications are contributing to liver damage, they should be discontinued under medical supervision.

In some cases, fatty liver can be caused by viral hepatitis C. For such cases, antiviral therapy is crucial alongside liver-protecting treatments. When liver enzymes are elevated, anti-inflammatory and liver-supportive medications like glycyrrhizin compounds may be prescribed. If bilirubin levels rise, medications such as S-adenosylmethionine (SAMe) and ursodeoxycholic acid (UDCA) can help improve liver and bile function.

In summary, fatty liver disease can indeed affect liver function markers, especially as the condition progresses. Early diagnosis and targeted treatment are key to preventing further liver damage and improving overall health outcomes. Regular monitoring of liver enzymes and working closely with a healthcare provider can help manage and potentially reverse liver damage caused by fatty liver disease.