Late Stage Liver Cancer Symptoms

The primary symptoms of late stage liver cancer include liver pain, fatigue, weight loss, jaundice, and abdominal fluid buildup, among others. Below is a detailed overview:

1. Liver Pain: One of the most common symptoms is pain in the liver area, often described as a dull, persistent ache or a feeling of fullness. As the tumor grows rapidly, it can stretch the liver's capsule, causing discomfort that may radiate to the right shoulder or back. Tumors growing toward the back may cause lower back pain. Sudden, severe abdominal pain may indicate a possible tumor rupture.

2. Jaundice: This condition, characterized by yellowing of the skin, eyes, and urine, occurs when the cancer presses on or invades the bile duct, leading to bile duct obstruction. It is a clear sign of advanced liver dysfunction due to tumor progression.

3. Digestive System Issues: Symptoms such as reduced appetite, indigestion, nausea, vomiting, and diarrhea may occur. These signs are often non-specific and can be easily overlooked, especially in the early stages of advanced disease.

4. Symptoms Related to Metastasis: If the cancer spreads to other parts of the body, additional symptoms may appear depending on the affected area. Bone metastasis can lead to localized pain, swelling, and even fractures. Lung involvement may cause shortness of breath. In the final stages, patients may also experience persistent low-grade fever, abdominal bloating, swelling in the lower limbs, significant weight loss, and general weakness — all signs of severe physical deterioration.

Recognizing these symptoms early and seeking medical attention can help improve the quality of life and support timely management decisions for patients with advanced liver cancer.