Is the Tumor Marker Elevated in Stomach Cancer?

Tumor markers such as CEA, CA724, and CA199 are commonly used to help detect and monitor various types of cancers, including gastric cancer. In many cases, patients with stomach cancer may show elevated levels in one or more of these markers. However, it's important to note that not all individuals diagnosed with gastric cancer will have high tumor marker levels.

Even in advanced or metastatic stomach cancer, some patients may still present with normal marker levels. On the flip side, elevated tumor markers don't always point to gastric cancer, as they can also be influenced by other conditions or cancers.

It's crucial to understand that current tumor markers are not 100% specific or sensitive for diagnosing gastric cancer. Therefore, combining multiple markers—such as CA199, CEA, and CA724—can improve the accuracy and sensitivity of detection. However, a definitive diagnosis should never rely solely on blood tests.

Gastroscopy and histopathological examination remain the gold standard for diagnosing stomach cancer. While tumor markers provide valuable insights, especially in monitoring treatment response or recurrence, they should be used in conjunction with clinical evaluations and imaging studies.

In summary, while elevated tumor markers can be a useful indicator, they are not conclusive evidence of gastric cancer. A comprehensive diagnostic approach that includes endoscopy and biopsy is essential for an accurate diagnosis.