Mr. Zhao Successfully Manages Advanced Gastric Cancer Through Medical Treatment

Early Symptoms and Diagnosis

In this case, Mr. Zhao, a 48-year-old male, visited our hospital due to persistent symptoms including nausea, stomach pain, bloating, and loss of appetite. He also reported fatigue and dizziness. Upon initial consultation, his vital signs were stable, and physical examination revealed no abnormalities. Further diagnostic tests were conducted, including a gastroscopy, which identified thickening of the gastric wall and a cauliflower-like growth in the antrum. A biopsy confirmed the presence of gastric adenocarcinoma. Based on these findings, he was admitted for further evaluation and staging.

Staging and Treatment Planning

A PET-CT scan revealed irregular thickening of the gastric wall with high FDG uptake, indicating advanced cancer with serosal invasion and peritoneal metastasis. As a result, Mr. Zhao was diagnosed with Stage IV gastric adenocarcinoma. Given the advanced nature of the disease and the presence of distant metastasis, surgical intervention was not considered beneficial. Instead, a systemic chemotherapy regimen was recommended to control tumor progression.

Chemotherapy Regimen and Patient Response

Mr. Zhao underwent six cycles of chemotherapy using a combination of nab-paclitaxel, oxaliplatin, and oral S-1 (Tegafur/Gimeracil/Oteracil). The first cycle was completed during a 15-day hospital stay. During treatment, he experienced mild nausea and vomiting, which improved after consuming sour foods such as cherry tomatoes and plums. No severe adverse effects were reported, and his overall tolerance to the regimen was good. Follow-up evaluations showed no tumor progression, and his condition remained stable.

Key Recommendations for Patients Undergoing Chemotherapy

To support recovery and minimize side effects, Mr. Zhao was advised to:

Maintain a light, easily digestible diet rich in fruits and vegetables, incorporating sour foods to help manage nausea.

Stay emotionally balanced and avoid stress or anxiety, which can impact immune function.

Monitor any new or worsening symptoms and seek medical attention promptly.

Take precautions to prevent infections, as chemotherapy can weaken the immune system.

Outcomes and Long-Term Outlook

Despite the advanced stage of his disease, Mr. Zhao responded well to the chemotherapy regimen. His tumor remained under control, and his quality of life improved significantly. This case demonstrates that even in advanced gastric cancer, timely and appropriate medical intervention can lead to meaningful disease control and better patient outcomes.

Conclusion

Advanced gastric cancer, particularly with metastatic spread, presents significant treatment challenges. However, systemic therapies such as chemotherapy can offer effective disease management and improved quality of life. Patients should remain proactive in seeking medical care and follow their treatment plans closely to achieve the best possible results.