Life Expectancy for Advanced Gastric Cancer with Liver Metastasis Without Treatment

Patients diagnosed with advanced gastric cancer that has metastasized to the liver typically survive between 6 to 12 months without treatment. However, those with better nutritional status and overall health may live for more than a year. Liver metastasis indicates that cancer has significantly progressed, with multiple cancerous lesions likely already present in the liver and possibly other areas of the abdominal cavity.

At the time of diagnosis, these additional metastases may not be detectable through imaging or other diagnostic tools. Over time, symptoms may progressively worsen. As the number of liver metastases increases, patients may experience abnormal liver function, potentially leading to liver failure. Other complications may include coagulation disorders, which can result in internal bleeding or hemorrhaging within the abdominal cavity.

If peritoneal seeding occurs alongside liver metastasis, patients may develop ascites, partial bowel obstruction, and abdominal pain. These symptoms often lead to a reduced ability to eat and digest food, further deteriorating the patient's nutritional status. As the condition progresses, severe weight loss and muscle wasting—known as cachexia—can develop, along with electrolyte imbalances.

These systemic effects significantly impact quality of life and contribute to a decline in overall survival. Timely palliative interventions may help manage symptoms and improve comfort, even in the absence of curative treatment.