New Treatment Options for Advanced Gastric Cancer

In recent years, significant progress has been made in the development of new drugs, particularly targeted therapies and immunotherapies, offering new hope for patients with advanced gastric cancer. Genetic testing is now a crucial step for late-stage patients, as it helps identify specific gene mutations that may be driving the cancer. If a mutation is found, targeted therapy could be an effective treatment option, tailored to the individual's unique cancer profile.

Immunotherapy has also emerged as a promising approach in treating advanced gastric cancer. Drugs like pembrolizumab (Keytruda) have demonstrated notable efficacy, especially when used in combination with chemotherapy. Clinical studies show that combining immunotherapy with traditional chemotherapy can extend median survival to approximately 15 months, which is a significant improvement compared to chemotherapy alone. This combination therapy is often considered for patients who are not candidates for surgery or who have experienced recurrence after initial treatment.

Advanced gastric cancer, which refers to cancer that cannot be completely removed by surgery or has returned after treatment, remains a major health challenge. In such cases, systemic chemotherapy has traditionally been the mainstay of treatment. However, the response to chemotherapy alone is often limited, prompting the need for more effective strategies such as targeted therapy and immunotherapy.

Gastric cancer is among the most common and deadliest cancers in China, ranking in the top three for both incidence and mortality. While early detection and treatment lead to better outcomes, patients diagnosed at an advanced stage typically face a poorer prognosis. Nevertheless, with the evolution of modern medicine, multiple lines of treatment—first-line, second-line, and even third-line therapies—are now available, helping to prolong survival and improve quality of life.

In conclusion, although advanced gastric cancer presents significant challenges, modern oncology offers a range of therapeutic options that can improve both survival and well-being. Patients are encouraged to work closely with their medical team to explore personalized treatment plans based on their specific condition and genetic profile.