How Long Does It Take for Verrucous Gastritis to Progress to Stomach Cancer?

Verrucous gastritis, also known as varioliform gastritis or chronic non-atrophic gastritis, is a unique type of gastric inflammation that is classified as a precancerous condition. While the progression from verrucous gastritis to stomach cancer typically takes several years, studies suggest that the natural course of the disease can range between 3 to 5 years if left untreated. Without proper medical intervention, there is a potential risk that this condition may evolve into gastric cancer over time.

This condition is characterized by flat, wart-like elevations on the surface of the stomach lining, which can appear granular or ulcerated, with signs of surface erosion or inflammation. These features are typically identified during a gastroscopic examination.

The development of verrucous gastritis is often linked to long-term dietary irregularities, chronic gastritis, and infection with Helicobacter pylori (H. pylori). When diagnosed through endoscopy, it is crucial to test for H. pylori infection. If present, patients are usually referred to a gastroenterologist for appropriate anti-H. pylori therapy and a biopsy to assess the severity of the condition.

In cases where intestinal metaplasia or dysplasia is detected alongside verrucous gastritis, more aggressive treatment may be necessary. Endoscopic submucosal resection or other endoscopic interventions can be performed to remove affected tissue and reduce the risk of cancer progression. Early detection and treatment are key to preventing the transformation of verrucous gastritis into stomach cancer. Regular follow-up and monitoring are strongly recommended for patients with this condition to ensure timely intervention if any malignant changes occur.