Common Medications for Colitis Treatment

Colitis is a broad term that refers to inflammation of the colon, and it can be caused by a variety of factors. When diarrhea is caused by increased intestinal motility—meaning the intestines contract too quickly—medications such as Pinaverium Bromide or Trimedat (Trimebutine) can help regulate gut movement. These are often combined with probiotics like Bifidobacterium to restore healthy gut flora, which is especially beneficial for chronic digestive disorders that lead to diarrhea. Kaolin or Smectite, also known as dioctahedral smectite, can form a protective layer across the entire gastrointestinal mucosa, helping to absorb toxins and protect the colon lining. This makes it effective for general chronic colitis and long-term diarrhea symptoms.

In the case of ulcerative colitis, a more specific and serious type of inflammatory bowel disease, common symptoms include mild to moderate abdominal pain, rectal bleeding, and a persistent urge to have a bowel movement even after just having one—a condition known as tenesmus. During a colonoscopy, doctors typically observe widespread, shallow ulcers starting from the rectum and extending upwards, along with the disappearance of normal vascular patterns. Blood in the stool is often the most noticeable symptom.

If ulcerative colitis is suspected, it is crucial to seek professional diagnosis and treatment at a hospital. One of the most commonly prescribed and effective medications is Mesalazine (also known as mesalamine), which has a well-established safety profile and is highly effective in reducing inflammation. Once diagnosed, patients must follow a carefully managed treatment plan, including dose adjustments and maintenance therapy, all of which should be supervised by a specialist. Self-adjusting medication without medical guidance is strongly discouraged. Proper medical supervision ensures long-term control of the disease and minimizes the risk of flare-ups or complications.