Can Reflux Esophagitis Be Treated Effectively with Domperidone?

Domperidone, also known by the brand name Motilium, can help alleviate symptoms of reflux esophagitis, especially when used in combination with acid-suppressing medications. While it may provide some relief on its own, studies and clinical practice suggest that combining it with proton pump inhibitors (PPIs) such as omeprazole or rabeprazole significantly improves treatment outcomes. These medications work by reducing the amount of acid produced in the stomach, which in turn helps reduce irritation and inflammation in the esophagus.

When domperidone is not effective enough, doctors may recommend alternative prokinetic agents such as mosapride or cisapride. These medications enhance gastrointestinal motility, helping the stomach empty more quickly and reducing the likelihood of acid reflux episodes.

Lifestyle and dietary modifications are also essential for managing reflux esophagitis. Patients are advised to avoid overeating and instead eat smaller, more frequent meals. Maintaining a healthy weight, quitting smoking, and avoiding alcohol can also have a significant impact on symptom relief. Certain foods and beverages, such as high-fat meals, strong tea, coffee, and chocolate, should be avoided as they can trigger acid reflux.

Following a full course of prescribed treatment is crucial for long-term recovery. In cases where standard treatments are not effective or symptoms frequently return, alternative therapies such as acupuncture or physiotherapy under the guidance of a qualified traditional Chinese medicine (TCM) practitioner may be considered. However, it's important to consult with a licensed TCM professional to ensure safe and appropriate treatment.

In conclusion, while domperidone can play a role in managing reflux esophagitis, it works best when combined with other medications and lifestyle changes. Always consult with a healthcare provider to determine the most suitable treatment plan for your condition.