Common Medications Used to Treat Reflux Esophagitis

Reflux esophagitis is a condition caused by the backflow of stomach acid into the esophagus, leading to inflammation and discomfort. Proper treatment often involves lifestyle changes combined with specific medications designed to reduce acid production, protect the esophageal lining, and improve digestive motility.

Acid-Suppressing Medications

One of the most effective ways to treat reflux esophagitis is by reducing stomach acid production. The following types of medications are commonly prescribed:

1. Proton Pump Inhibitors (PPIs): These include omeprazole, lansoprazole, pantoprazole, rabeprazole, and esomeprazole. PPIs work by blocking the action of proton pumps in the stomach lining, which are responsible for producing acid. For optimal results, these medications should be taken 15–30 minutes before meals, aligning their peak effect with the acid surge that occurs after eating.

2. Potassium-Competing Acid Blockers (P-CABs): Vonoprazan falls into this category and is known for its rapid and long-lasting acid suppression capabilities.

Antacids and Mucosal Protective Agents

In addition to reducing acid production, it's also important to neutralize existing stomach acid and support the healing of the esophageal lining. Antacids such as magnesium aluminum carbonate chewable tablets can help neutralize gastric acid and provide fast relief from heartburn and other symptoms. They may also aid in the healing of irritated mucosal tissue.

Motility-Enhancing Medications

Some patients with reflux esophagitis experience delayed gastric emptying or poor esophageal motility. In such cases, doctors may recommend prokinetic agents like itopride or mosapride. These drugs help strengthen the muscles of the digestive tract, thereby reducing the frequency and severity of acid reflux episodes.

By combining these medication strategies with dietary and lifestyle adjustments, many individuals find significant improvement in their reflux symptoms and overall quality of life. Always consult a healthcare provider before starting any new treatment regimen.