Reflux Esophagitis Grade B: Effective Treatment Strategies

Managing reflux esophagitis Grade B typically involves a combination of lifestyle modifications and medical treatments to reduce symptoms and promote healing. Here are the most commonly recommended approaches:

1. Lifestyle and Dietary Adjustments

Making changes to daily habits and diet can significantly impact the severity and frequency of reflux symptoms. Patients should avoid foods that trigger or worsen acid reflux, such as spicy dishes, high-fat meals, and sweets. Eating large portions or lying down immediately after a meal should also be avoided, as these actions can increase the likelihood of acid regurgitation into the esophagus.

2. Acid Suppression Medications

Proton pump inhibitors (PPIs) are the cornerstone of pharmacological treatment for reflux esophagitis. These medications target the H+-K+ ATPase enzyme in gastric parietal cells, effectively reducing stomach acid production. Commonly prescribed PPIs include rabeprazole, pantoprazole, omeprazole, and lansoprazole. In recent years, newer acid-suppressing drugs such as potassium-competitive acid blockers (P-CABs), like vonoprazan, have shown promising results in controlling gastric acidity.

3. Combination Therapy for Enhanced Relief

If PPIs alone do not provide sufficient symptom relief, additional medications may be introduced. Gastroprotective agents such as magnesium aluminum carbonate chewable tablets help form a protective layer over the gastric mucosa, aiding in tissue repair and neutralizing excess acid. Prokinetic drugs, including trimebutine and itopride, enhance gastrointestinal motility and help prevent the backflow of stomach contents, thereby alleviating discomfort associated with gastroesophageal reflux disease (GERD).