Non-Atrophic Gastritis and Its Potential for Cancer Development

Non-atrophic gastritis, also known as superficial gastritis, is a type of chronic gastritis characterized by chronic inflammation of the gastric mucosa caused by various factors. The clinical symptoms are often non-specific, and diagnosis typically relies on endoscopic examination and histopathological biopsy.

It is common for most adults to have mild, inactive chronic superficial gastritis, which can be considered a physiological mucosal immune response and generally does not require pharmacological treatment. While the prognosis for chronic non-atrophic gastritis is generally favorable, it may carry a risk of malignant transformation. In the progression from chronic inflammation to gastric cancer, conditions such as metaplasia, atrophy, and dysplasia are recognized as precancerous states.

Intestinal metaplasia is often irreversible, although some cases of atrophy may improve or even reverse with appropriate interventions. While atypical hyperplasia can also be reversible in some instances, severe cases have a higher likelihood of progressing to cancer.

Patients should be mindful of maintaining a regular and balanced diet, consuming a variety of nutrients, and avoiding moldy foods. It is advisable to limit intake of smoked, pickled, or nitrate-rich foods, and instead opt for fresh, wholesome meals. Additionally, individuals should avoid overly coarse, spicy, or strongly seasoned foods, reduce long-term alcohol consumption, quit smoking, and maintain good mental health and sufficient sleep to prevent exacerbation of non-atrophic gastritis.

In conclusion, non-atrophic gastritis does carry a potential risk of cancer development. Therefore, patients diagnosed with this condition, especially those with precancerous lesions such as metaplasia, atrophy, or dysplasia, should undergo regular endoscopic follow-ups to monitor any changes in their condition and ensure timely medical intervention.