How to Treat Chronic Gastritis with Helicobacter pylori Infection

Chronic gastritis associated with Helicobacter pylori (H. pylori) infection typically requires a comprehensive medical treatment plan. The most effective approach is a 14-day quadruple therapy regimen, which includes two different antibiotics such as amoxicillin, clarithromycin, furazolidone, metronidazole, or tetracycline. These antibiotics work together to target and eliminate the bacterial infection.

In addition to antibiotics, patients are prescribed a proton pump inhibitor (PPI), such as omeprazole, pantoprazole, or rabeprazole. These medications help reduce stomach acid production, allowing the gastric lining to heal more effectively during treatment. A bismuth-containing compound like colloidal bismuth subcitrate is also added to the regimen, as it helps protect the stomach lining and enhances the eradication of H. pylori.

It's important to complete the full course of treatment to achieve the best results. Studies show that following the quadruple therapy for the recommended duration significantly increases the likelihood of successfully eliminating H. pylori. Failure to complete the regimen may lead to antibiotic resistance and a recurrence of symptoms.

Beyond medication, preventing reinfection or transmission is crucial. H. pylori can spread through saliva and the fecal-oral route, so maintaining good hygiene practices is essential. Washing hands regularly, especially before eating and after using the bathroom, and avoiding shared utensils or food can help reduce the risk of infection. Practicing safe eating habits, such as consuming well-cooked food and drinking clean water, also plays a key role in prevention.

If symptoms persist after completing treatment, it's advisable to consult a healthcare provider for further evaluation and possible retreatment options. Early diagnosis and proper management are vital in treating chronic gastritis caused by H. pylori.