Common Medications for Indigestion and How They Work

Indigestion, also known as dyspepsia, can be uncomfortable and disruptive to daily life. Fortunately, several types of medications are available to help manage symptoms and promote digestive comfort. Understanding how each category of medication works can help you make informed decisions in consultation with your healthcare provider.

Acid-suppressing medications are commonly used to reduce stomach acid production. Examples include H2 blockers like ranitidine and proton pump inhibitors such as omeprazole. These medications are especially helpful when indigestion is related to excess acid or conditions like gastroesophageal reflux disease (GERD).

Another group of medications is antacids, which work by neutralizing stomach acid. Common antacids include aluminum hydroxide and hydrotalcite. These provide quick, short-term relief for mild symptoms and are often available over the counter.

For individuals experiencing delayed gastric emptying, prokinetic agents may be recommended. Drugs like mosapride and itopride help improve gastrointestinal motility, reducing symptoms such as bloating and early satiety.

In addition, mucosal protective agents like sucralfate can be used to shield the stomach lining from irritation. These medications form a protective barrier that helps the stomach heal and prevents further discomfort.

Other treatment options may include digestive enzymes to assist with food breakdown, or probiotics and other microbiome-supporting supplements to promote a healthy balance of gut bacteria. If a patient tests positive for Helicobacter pylori infection, a course of antibiotics may be necessary to eliminate the bacteria, which is often a root cause of recurring indigestion.

It's important to note that while these medications can be effective, the right treatment plan depends on the underlying cause of indigestion. Always consult with a healthcare professional to determine the most appropriate medication, dosage, and duration of treatment for your specific condition.