Can People with Egg Allergies Receive the Flu Vaccine?

Understanding the Connection Between Egg Allergies and Flu Vaccines

Historically, flu vaccines have been produced using a method that involves growing influenza viruses in chicken embryos. The virus is injected into the allantoic cavity of fertilized eggs, where it multiplies before being harvested, inactivated, and purified for use in vaccines. Because this process leaves trace amounts of egg protein in the final product, there has long been concern about administering flu shots to individuals with egg allergies.

Updated Medical Guidelines on Egg Allergy and Vaccination

However, recent research and updated guidelines from major health organizations—including the Centers for Disease Control and Prevention (CDC) and the American Academy of Allergy, Asthma & Immunology (AAAAI)—now confirm that people with egg allergies can safely receive the seasonal flu vaccine. Studies show that the amount of ovalbumin (a major egg protein) in modern flu vaccines is extremely low and highly unlikely to trigger an allergic reaction, even in those with severe egg sensitivity.

For most individuals with egg allergy, including those who have experienced hives or mild reactions after eating eggs, the standard flu shot is considered safe and does not require special precautions beyond routine post-vaccination monitoring.

Who Should Still Exercise Caution?

While the vast majority of egg-allergic patients can be vaccinated without issue, those who have had a previous anaphylactic reaction to a flu vaccine—or who are known to be allergic to any other component of the vaccine—should consult an allergist before vaccination. In rare cases, healthcare providers may recommend observation for 30 minutes after injection, especially if there's a history of severe allergic responses.

Other Contraindications for Flu Vaccination

Beyond allergies, certain medical conditions also affect eligibility for the flu shot. Individuals experiencing acute febrile illness or an active flare-up of a chronic disease should delay vaccination until they recover. This precaution helps distinguish between symptoms caused by the illness and potential vaccine side effects.

Pregnant women were once advised against receiving live attenuated vaccines, but current data supports the safety and effectiveness of inactivated flu vaccines during pregnancy. In fact, health authorities now strongly recommend flu vaccination for pregnant women, as they are at higher risk for severe complications from influenza.

Best Practices After Receiving the Flu Shot

Regardless of allergy status, it's recommended that all recipients remain at the vaccination site for at least 15 to 30 minutes after injection. This allows medical staff to respond quickly in the unlikely event of an immediate hypersensitivity reaction. Most side effects, such as soreness at the injection site or mild fatigue, are temporary and resolve within a day or two.

In summary, having an egg allergy is no longer a barrier to getting your annual flu vaccine. With advanced manufacturing techniques and strong clinical evidence supporting safety, millions of people with egg sensitivities can now protect themselves—and their communities—from seasonal influenza.