Young Man Successfully Treats Bronchitis with Combination Therapy Including Cefixime

Acute bronchitis can significantly disrupt daily life, especially in young adults engaged in academic and social activities. This case highlights the successful treatment of a 21-year-old male patient diagnosed with acute bronchitis following exposure to outdoor environmental triggers. After presenting with persistent cough, sputum production, and shortness of breath, he was effectively managed using a combination of oral antibiotics, mucolytics, bronchodilators, and inhaled corticosteroids. Within one week of targeted therapy, his symptoms markedly improved, allowing him to return to normal campus life. Follow-up over the next month confirmed full recovery without complications.

Patient Profile & Clinical Diagnosis

Age: 21 years oldGender: MaleDiagnosis: Acute bronchitisHospital: The First Affiliated Hospital of Anhui Medical UniversityDate of Visit: June 2022Treatment Plan: Oral medications (Cefixime granules, Ambroxol hydrochloride dispersible tablets, Doxofylline tablets) combined with nebulized therapy (Budesonide suspension for inhalation, Ipratropium bromide and fenoterol solution)Treatment Duration: 7 days of home-based treatment followed by 1 month of outpatient monitoringOutcome: Significant symptom relief and complete disease resolution

Initial Consultation: Recognizing the Signs of Infection

The patient, a university student, came to our clinic complaining of worsening respiratory symptoms after participating in outdoor school activities. He initially experienced dry cough and productive sputum, which he attempted to self-treat with over-the-counter syrup (Kejizhi Syrup). However, his condition did not improve—instead, it progressed to include wheezing and increased respiratory discomfort that began interfering with sleep and concentration.

Upon physical examination, vital signs were stable, but auscultation revealed coarse breath sounds and audible rhonchi in both lung fields. A chest CT scan showed findings consistent with bronchial inflammation, prompting a diagnosis of acute bronchitis. Blood tests further supported this diagnosis, showing elevated white blood cell count and increased neutrophil percentage—key markers of bacterial infection. Given the clinical presentation and lab results, we concluded that antibiotic intervention was necessary alongside symptomatic management.

Treatment Approach: Targeted Multi-Drug Strategy

To address both the underlying infection and the distressing symptoms, a comprehensive treatment plan was developed. Cefixime granules, a third-generation cephalosporin antibiotic, were prescribed to combat bacterial pathogens by inhibiting cell wall synthesis in susceptible organisms. This choice was based on its broad-spectrum efficacy and favorable safety profile in young adults.

In parallel, supportive therapies were introduced to enhance comfort and accelerate recovery:

• Ambroxol hydrochloride was used to break down thick mucus and facilitate easier expectoration.
• Doxofylline, a xanthine derivative with fewer side effects than theophylline, helped relax airway smooth muscles and relieve wheezing.
• For localized anti-inflammatory and bronchodilator effects, budesonide suspension and ipratropium bromide/fenoterol solution were administered via nebulization twice daily.

The patient received clear instructions on proper medication use, including dosage timing, inhaler technique, and the importance of completing the full course even if symptoms resolved early.

Positive Treatment Response Within Days

A follow-up phone call seven days after initiating therapy revealed encouraging progress. The patient reported noticeable improvement within 48–72 hours: sputum volume decreased, and breathing became easier. By day five, most symptoms had subsided entirely. There was no fever, chest tightness, or fatigue noted during the call.

One month later, during an outpatient visit, the patient appeared healthy and active, with no recurrence of cough or dyspnea. Lung auscultation was clear, and he had resumed regular academic routines without limitations. These outcomes confirmed not only effective symptom control but also complete clinical recovery.

Ongoing Care and Prevention Tips

While the treatment was successful, long-term wellness depends on preventive habits. I advised the patient—and recommend to others facing similar conditions—the following lifestyle strategies:

Nutrition Matters: During recovery, focus on light, nutrient-dense meals rich in vitamins and protein. Fresh fruits, vegetables, lean meats, and whole grains support immune function and tissue repair.

Stay Warm and Protected: Sudden temperature changes can trigger airway irritation. Dress appropriately for weather shifts, especially in spring and fall when respiratory infections peak.

Medication Adherence Is Key: Never stop or adjust prescribed medications without consulting your doctor. Premature discontinuation of antibiotics increases the risk of relapse and antimicrobial resistance.

Maintain Healthy Routines: Prioritize sleep, avoid all-night study sessions, stay hydrated, and minimize stress—all of which contribute to stronger immunity and faster healing.

Clinical Reflection: Why Early Intervention Works

Bronchitis remains one of the most common lower respiratory tract conditions seen in primary care. Often triggered by viral or bacterial infections, as well as environmental irritants like pollen or cold air, it manifests through persistent cough, mucus production, and sometimes wheezing. Left untreated, it may lead to prolonged illness or secondary complications such as pneumonia.

This case underscores the value of timely diagnosis and a multi-modal treatment strategy. By combining antibacterial action with airway clearance and bronchodilation, we achieved rapid symptom relief and prevented progression. It also highlights the danger of self-medication without professional guidance—early reliance on non-prescription syrups delayed appropriate care in this instance.

Ultimately, recognizing the warning signs and seeking prompt medical attention makes all the difference. With the right therapeutic approach, even disruptive respiratory illnesses like bronchitis can be resolved efficiently and safely.