Common Causes of Persistent Upper Middle Abdominal Pain

Persistent discomfort or mild pain in the upper middle abdomen can be caused by a variety of medical conditions. This type of pain often relates to internal organs such as the stomach, intestines, liver, gallbladder, and pancreas. If someone experiences this symptom for an extended period, it is strongly recommended they visit a gastroenterology department at a local hospital for diagnostic tests like endoscopy or stool analysis. Identifying the root cause is essential before beginning any targeted treatment under professional guidance.

Gastrointestinal Issues

Conditions like gastritis or gastroenteritis may lead to ongoing pain in the upper middle abdomen. These issues often occur due to consuming contaminated food or water, allowing bacteria or viruses to enter the digestive system. Inflammation from these infections irritates the mucous lining of the stomach and intestines, resulting in symptoms such as persistent abdominal pain, nausea, vomiting, loss of appetite, and bloating. Doctors may prescribe antibiotics like Levofloxacin or Ciprofloxacin to treat bacterial causes of these conditions.

Liver-Related Conditions

Liver tumors, whether benign or malignant, can also cause discomfort in the upper abdomen. As a tumor grows rapidly, it can stretch the liver capsule, leading to pain—typically on the right side. However, if the tumor is located in the left lobe of the liver, it may cause pain in the upper middle abdomen. Additional symptoms may include bloating and belching. Surgical removal of the affected area is often considered depending on the severity and location of the tumor.

Gallbladder and Biliary Tract Disorders

Gallbladder inflammation, commonly known as cholecystitis, is frequently linked to gallstones that block the bile ducts and damage the gallbladder lining. Although the gallbladder is located in the upper right quadrant of the abdomen, pain can radiate toward the center over time. This shift may result in persistent discomfort in the upper middle abdomen, often accompanied by nausea, vomiting, and reduced appetite. Treatment options may involve medications such as Ursodeoxycholic acid or Cefixime to manage inflammation and dissolve gallstones.

Pancreatic Conditions

Acute pancreatitis is another potential cause of upper middle abdominal pain. Often triggered by heavy alcohol consumption or overeating, this condition involves excessive production of pancreatic enzymes that cannot properly drain into the intestine. As a result, the pancreas begins to digest itself, causing intense pain in the upper abdomen. Other symptoms typically include nausea and vomiting. To reduce enzyme secretion and ease symptoms, doctors may administer medications like Somatostatin or Octreotide.

During treatment, patients must follow their physician's instructions carefully and avoid self-medicating. Additionally, maintaining a light and easily digestible diet is crucial. Avoiding spicy, fatty, or processed foods—such as chips or fried dough sticks (youtiao)—can help prevent worsening of symptoms and promote faster recovery.