What To Do If You Experience Constipation After Taking Acetaminophen With Oxycodone

Constipation is a common and non-serious side effect that may occur after taking acetaminophen with oxycodone. This is primarily due to the drug's effect on stimulating gastrointestinal smooth muscle, which slows intestinal motility. Unfortunately, this symptom does not typically improve with continued use of the medication. However, there are several effective strategies—ranging from lifestyle adjustments to medical interventions—that can help manage constipation caused by this medication.

1. Dietary Adjustments for Mild Constipation

For individuals experiencing mild constipation, it is generally safe to continue taking the medication while making specific dietary changes. Increasing daily water intake and consuming more high-fiber foods such as oats, celery, and apples can significantly improve bowel movements. These natural remedies often provide gentle relief without the need for additional medications.

2. Medical Treatments for Moderate to Severe Cases

If constipation becomes severe or uncomfortable, it's important to seek medical advice promptly. A healthcare provider may recommend over-the-counter or prescription medications designed to soften stools or stimulate bowel movement. Examples include bisacodyl, lactulose oral solution, and polyethylene glycol 4000 powder. In some cases, a doctor might suggest using a phosphate-based solution or normal saline enema for immediate relief. Additionally, if slow gastrointestinal motility is suspected, medications like metoclopramide (Reglan) may be prescribed to restore normal digestive function.

3. Surgical Intervention in Extreme Situations

In rare cases where constipation leads to bowel obstruction, accompanied by symptoms such as frequent vomiting or intense abdominal pain, immediate medical attention is essential. At this stage, discontinuation of the medication is necessary, and hospitalization may be required. Depending on the severity of the blockage, surgical treatment could be considered to resolve the issue and prevent further complications.

Managing constipation while taking acetaminophen with oxycodone requires a proactive approach. Always consult your physician before starting any new treatment, especially when combining medications or considering invasive options.