Managing Cirrhosis-Related Ascites: Effective Strategies and Treatment Options
Cirrhosis-related ascites typically develops due to a combination of low protein levels in the blood (hypoalbuminemia) and fluid retention, particularly sodium and water. In most cases, the accumulated fluid in the abdominal cavity is classified as a transudate. However, if ascites persists for a long time or becomes infected—such as in spontaneous bacterial peritonitis—it may exhibit characteristics of an exudate.
One of the first steps in managing this condition involves dietary modifications, specifically limiting salt and fluid intake. It's generally recommended that patients consume less than 2 grams of sodium per day and restrict fluid intake to around 1 liter daily. These changes can significantly impact fluid balance and reduce further accumulation of ascites.
From a medical standpoint, treatment often includes intermittent albumin infusions to improve blood protein levels, diuretics such as spironolactone and furosemide to promote fluid excretion, and antibiotics when infection is suspected or confirmed. Monitoring urine output and weight changes are crucial during therapy—aiming for a gradual reduction, ideally no more than 2 kilograms per week, to avoid complications like renal impairment.
Patients should also be vigilant about physical symptoms, especially abdominal discomfort or swelling. Regular follow-ups with a healthcare provider and adherence to prescribed treatments are essential components of long-term management.
In more advanced cases, procedures like therapeutic paracentesis may be considered to remove large volumes of fluid under medical supervision. Additionally, lifestyle adjustments and early intervention can greatly enhance quality of life and reduce hospitalization risks.