What Is the Maximum Liver Stiffness Level in Cirrhosis?

When assessing liver elasticity, a stiffness value of 17.5 kPa or higher can be an indicator of cirrhosis. However, it's important to note that there is no defined upper limit for liver stiffness, and this measurement alone is not sufficient for a definitive diagnosis of cirrhosis. The accuracy of liver stiffness measurements can be influenced by several factors including liver cell inflammation, necrosis, edema, and jaundice.

Patients with jaundice may exhibit significantly elevated liver stiffness values. However, once the underlying condition improves and bilirubin levels return to normal, the stiffness reading often decreases as well. This highlights the dynamic nature of liver stiffness and the need to interpret results within a broader clinical context.

To accurately diagnose cirrhosis and assess its severity, healthcare providers must consider multiple diagnostic tools and tests such as liver function tests, complete blood count, ultrasound imaging of the liver, gallbladder, and spleen, and in some cases, computed tomography (CT) scans of the liver.

Relying solely on liver stiffness measurements can lead to misinterpretation. A comprehensive approach ensures a more accurate assessment of liver health and the presence of cirrhosis.