How Long Can a Person Live After Spleen Removal Due to Cirrhosis

For patients with cirrhosis, the life expectancy after spleen removal is generally similar to that of cirrhosis patients who have not undergone splenectomy. The primary purpose of removing the spleen in such cases is to reduce portal venous pressure and prevent potentially life-threatening bleeding from esophageal or gastric varices.

After spleen removal, patients often experience an increase in platelet count, which can raise the risk of blood clot formation. It is crucial to monitor and manage this elevated platelet level to prevent potentially dangerous venous thrombosis, especially in abdominal arteries, which can lead to severe complications like intestinal necrosis. In some cases, doctors may prescribe anticoagulant medications such as low molecular weight heparin or warfarin to help prevent clotting issues.

Despite the removal of the spleen, the underlying liver damage—characterized by the presence of regenerative nodules or "pseudolobules"—remains unchanged. This means that portal hypertension can persist and may even lead to recurrent variceal bleeding. As a result, ongoing monitoring and management of liver function and vascular complications are essential for long-term health outcomes.

In summary, while spleen removal can provide certain therapeutic benefits in cirrhosis patients, it does not alter the overall prognosis of liver disease. Comprehensive post-operative care, including anticoagulation therapy and regular surveillance for varices, is vital to improving quality of life and reducing mortality risks.