How to Deal with Multiple Cerebral Infarctions with Softening Foci

Multiple cerebral infarctions with softening foci may not present any clinical symptoms or signs in some patients. In such cases, specific treatment is generally not required. The main approach involves long-term secondary prevention to reduce the risk of future infarctions.

Key Treatment Strategies

From a clinical perspective, long-term oral administration of aspirin is commonly prescribed to inhibit platelet aggregation. Additionally, statins such as simvastatin, rosuvastatin, and atorvastatin are used to regulate lipid levels and stabilize atherosclerotic plaques. These medications play a crucial role in preventing further vascular events.

Managing Underlying Risk Factors

Controlling underlying risk factors is equally important. For patients with hypertension, calcium channel blockers like amlodipine or amlodipine besylate are often recommended to maintain stable blood pressure. In diabetic patients, first-line treatments typically include oral medications such as metformin and acarbose to manage blood sugar levels effectively. If oral medications are insufficient, subcutaneous insulin injections may be necessary to maintain blood glucose around 6 mmol/L.

Addressing Cognitive Decline

In some cases, patients may develop vascular dementia, characterized by memory impairment and cognitive decline. Clinically, treatment focuses on improving cerebral metabolism. Commonly prescribed drugs include oxiracetam, piracetam, and cytidine diphosphate-choline (CDP-choline), which help support brain function and slow cognitive deterioration.