Treatment Options for Cerebral Thrombosis

Thrombolytic Therapy

For patients diagnosed with cerebral infarction within the treatment time window, thrombolytic therapy remains a crucial option. This intervention helps dissolve blood clots and restore blood flow to affected areas of the brain. In many regions, rt-PA (recombinant tissue plasminogen activator) and urokinase are commonly administered under strict medical supervision to achieve optimal results.

Antiplatelet Therapy

When thrombolytic treatment isn't appropriate, antiplatelet therapy becomes the preferred approach for ischemic stroke patients without contraindications. Aspirin is typically recommended as the first-line medication to prevent further clot formation. For non-cardioembolic minor strokes occurring within the past 24 hours, dual antiplatelet therapy combining aspirin and clopidogrel may be prescribed, with treatment duration generally limited to three weeks.

Defibrinogenation Therapy

In specific cases where thrombolytics aren't suitable, defibrinogenation therapy could be considered after careful patient selection. This treatment proves particularly beneficial for individuals with elevated fibrinogen levels. Medications like batroxobin (a serine protease) are frequently used to reduce fibrinogen levels and improve blood flow.

Neuroprotective Strategies

Edaravone Treatment

Edaravone represents a key neuroprotective agent used in cerebral thrombosis management. As a potent antioxidant and free radical scavenger, it helps protect brain cells from oxidative damage during the critical post-stroke period.

Cerebral Circulation Improvement

Butylphthalide Application

Butylphthalide demonstrates effectiveness in promoting collateral circulation development, offering additional benefits for stroke patients. This compound helps improve blood flow to ischemic regions of the brain through alternative vascular pathways.

Plaque Stabilization and Cholesterol Management

Statins like atorvastatin and simvastatin play essential roles in preventing plaque rupture and reducing cholesterol levels. These medications not only lower lipid levels but also contribute to vascular health improvement and stroke recurrence prevention.

Comprehensive Disease Management

Effective treatment also involves careful management of associated conditions. Blood pressure and glucose levels should be monitored and controlled according to individual patient needs, with appropriate medications selected based on comprehensive medical evaluation.

Supportive Therapies

Additional treatment approaches include nerve nutrition support and blood circulation improvement strategies. Medications like mecobalamin can aid in nerve function recovery, while certain traditional formulations may complement standard therapies. Lifestyle modifications including complete tobacco cessation and alcohol abstinence prove crucial for recovery and prevention of recurrence.

Patients should always seek professional medical evaluation at certified healthcare facilities for accurate diagnosis and personalized treatment planning. Regular follow-up examinations help monitor progress and adjust interventions as needed. Dietary recommendations typically emphasize low-sodium, low-fat, and low-sugar meal plans to support overall vascular health and reduce future risk.