Primary Causes of Cirrhosis

Cirrhosis is a serious liver condition characterized by the replacement of healthy liver tissue with scar tissue, leading to impaired liver function. Understanding the primary causes of this disease is essential for prevention and early intervention. Below are the most common factors that contribute to the development of cirrhosis:

Viral Hepatitis Infection

One of the leading causes of cirrhosis is chronic viral hepatitis, particularly hepatitis B and, to a lesser extent, hepatitis C. In China, approximately one in every ten people lives with hepatitis B, significantly increasing the risk of long-term liver damage and subsequent cirrhosis.

Alcohol-Related Liver Disease

Excessive and prolonged alcohol consumption is another major contributor to cirrhosis. A detailed medical history often reveals heavy drinking or chronic alcohol abuse, which gradually damages liver cells and leads to scarring over time.

Nutritional Deficiencies

Poor nutrition can weaken the liver's ability to detoxify harmful substances in the body. When the liver is unable to perform this vital function effectively, it becomes more vulnerable to injury and fibrosis, which may progress to cirrhosis.

Exposure to Industrial Toxins

Certain industrial chemicals such as chloroform and nitrates have been linked to liver damage. Long-term exposure to these substances can trigger liver fibrosis, which may eventually develop into cirrhosis if left unchecked.

Circulatory Problems

Conditions like congestive heart failure can impair blood flow to the liver, causing congestion and increased pressure within liver veins. This buildup of blood can lead to chronic liver damage and the formation of scar tissue over time.