What Are the Effective Medications for Treating Chronic Gastric Ulcers?

Chronic gastric ulcers can significantly affect a person's quality of life, and understanding the right treatment is essential for recovery. One of the primary causes of gastric ulcers is Helicobacter pylori (H. pylori) infection, which damages the protective lining of the stomach. However, other factors such as certain medications, poor dietary habits, and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) can also contribute to ulcer development.

When it comes to medical treatment, there are several effective options available:

1. Acid-Suppressing Medications

Reducing stomach acid is a key part of ulcer treatment. Proton pump inhibitors (PPIs), such as omeprazole and lansoprazole, are commonly prescribed to lower acid production and allow the ulcer to heal. In addition, H2 receptor antagonists like cimetidine and ranitidine may be used to further control acid secretion.

2. Gastric Mucosal Protective Agents

These medications help protect the stomach lining and promote healing. Examples include colloidal bismuth pectin, bismuth subcitrate potassium, and sucralfate. These agents create a protective barrier over the ulcer, shielding it from digestive acids and allowing tissue repair.

3. Eradication Therapy for H. pylori

For ulcers caused by H. pylori infection, a combination therapy known as bismuth-based quadruple therapy is often recommended. This regimen includes a proton pump inhibitor, a bismuth-containing mucosal protector, and two different antibiotics—such as amoxicillin, clarithromycin, metronidazole, furazolidone, or levofloxacin. Completing the full course of antibiotics is crucial to eliminate the bacteria and prevent recurrence.

It's important to note that all medication choices should be made under the supervision of a qualified healthcare provider. Self-medication or incorrect use of drugs can lead to complications or reduced effectiveness of treatment. Consulting a gastroenterologist ensures a personalized and effective treatment plan tailored to your specific condition.