Acute Infective Endocarditis: Recognizing the Most Common Symptoms

One of the hallmark signs of acute infective endocarditis is the presence of persistent high fever. This type of fever often presents as either a remittent or intermittent pattern. In cases of remittent fever, patients may experience a continuous elevation in body temperature, often reaching as high as 39°C or even 40°C.

Understanding the Fever Patterns in Endocarditis

Remittent fever is characterized by sudden spikes in temperature, typically rising to between 39°C and 40°C, followed by a gradual return to normal levels. This cycle then repeats itself, often due to the release of bacteria into the bloodstream. The fever is a direct response of the immune system to these circulating pathogens.

The Role of Bacterial Release in Fever Development

The presence of bacterial vegetations on heart valves plays a critical role in this process. These localized growths can repeatedly rupture, releasing additional bacteria into the circulatory system. This ongoing bacterial dissemination contributes to the recurring nature of the fever, often accompanied by chills in many patients.

Key Symptoms to Watch For

Patients may also experience other systemic symptoms such as fatigue, muscle aches, and general malaise. The combination of high fever, chills, and unexplained fatigue should prompt medical evaluation, especially in individuals with pre-existing heart conditions or recent invasive procedures.