How to Identify Atrophic Gastritis

Atrophic gastritis is primarily diagnosed through endoscopic examination. During a gastroscopy, experienced physicians can observe distinct whitish patches on the gastric mucosa, which indicate significant atrophy of the gastric glands. In more advanced cases, the thinning of the mucosa allows for visible through of submucosal blood vessels, offering further evidence of the condition. However, visual assessment alone is not sufficient for a definitive diagnosis.

Endoscopic Evaluation and Key Observations
During the endoscopic procedure, doctors look for specific signs such as pale mucosa and reduced visibility of gastric folds. These visual cues suggest potential atrophy, but they must be confirmed with histological analysis.

The Importance of Biopsy and Histopathology
To confirm atrophic gastritis, tissue samples are taken from several areas of the stomach during the endoscopy. These biopsies are then sent to a pathology lab where trained specialists examine the tissue under a microscope. The presence of reduced or absent gastric glands, along with the loss of specialized cells in the mucosa, is crucial for diagnosing atrophic gastritis.

Pathological Confirmation Is Essential
Only through detailed histopathological evaluation can true atrophic changes be identified. This includes the assessment of glandular structure and the presence of intestinal metaplasia, which often accompanies chronic atrophic gastritis. A conclusive diagnosis relies heavily on these microscopic findings, making biopsy an indispensable part of the diagnostic process.