Most Common Medications That Can Cause Arrhythmias When Used in Excess

Medications used to treat arrhythmias can themselves cause irregular heartbeats when administered in excessive amounts. In some cases, this can lead to life-threatening cardiac conditions.

Antiarrhythmic Drugs With Toxic Potential

Digoxin, Quinidine, Amiodarone, and Propafenone are among the most commonly prescribed antiarrhythmic agents that may trigger cardiac rhythm disturbances when overdosed. These medications are designed to stabilize heart rhythm, but paradoxically, they can induce arrhythmias when used improperly.

Beta-Blockers and Heart Rate Regulation

Excessive Use of Beta-Blockers

Overuse of beta-blockers often results in sinus bradycardia, a condition characterized by an abnormally slow heart rate. Additionally, improper administration of cardiac stimulants such as epinephrine, isoproterenol, and dopamine can also provoke arrhythmias, especially in patients with underlying heart conditions.

Diuretics and Electrolyte Imbalance

Non-potassium-sparing diuretics like furosemide can cause severe electrolyte imbalances when used long-term without proper monitoring. This often leads to hypokalemia (low potassium) and hypocalcemia (low calcium), which significantly increase the risk of malignant arrhythmias—potentially fatal heart rhythm disorders.

Mental Health Medications and Cardiac Risks

Antidepressants and Anti-Anxiety Drugs

Chronic overuse of psychiatric medications, including antidepressants and anti-anxiety drugs, has also been linked to cardiac rhythm disturbances. It's crucial for patients to follow medical guidance precisely to minimize adverse effects and ensure safe medication use.